Essay On CRISPR Casr - 787 Words

In the year 1987, a scientific named Yoshizumi Ishino discover five upstream sequences of repeated bases with unique spacer DNAs between them in iap gene in E. coli. Later additional research found that many bacteria (40%) and archaea (90%) contained similar regions. This region was named Clustered Regularly Interspaced Palindromic Repeats in 2002. The uses of CRISPR cas9 can revolution the world of medicine. The development of this technique can be the key to cure many diseases. According to GeneScript â€Å"CRISPR/Cas9-mediated gene editing is a powerful technique that allows you to create knock-in/out mutations in any gene and any cell.† In addition, according to New Englang Biolabs â€Å"Three types of CRISPR mechanisms have been identified,†¦show more content†¦Through its use, science will be able to increase human lifespan by slowing down the shortening of telomeres, also boosting intelligence, and as mention earlier cure diseases such as HIV/AIDS, hemophilia, sickle cell anemia and several forms of cancer, Huntington’s Tay-Sachs and many more deadly inherited diseases. However, concerns have been raised on how precise this machinery is on cutting of adding sequence to the genome. In that matter of fact, the opposite site argument is based on the fact that a malfunction in the process can create more harm than good. Also, there is a debate on the ethical part of the system. To test the efficiency of CRISPR Cas9 on human, scientific will have to use human embryos. On Universiteit Utrecht website, it is said that â€Å"although CRISPR has much to offer, some scientists are worried that the field’s breakneck pace leaves little time for addressing the ethical and safety concerns such experiments can raise. The problem was thrust into the spotlight in April, when news broke that scientists had used CRISPR to engineer human embryos. The embryos they used were unable to result in a live birth, but the report has generated heated debate over whether and how CRISPR should be used to make heritable changes to the human genome.† Otieno MO is a lso stated in her article stated, â€Å"CRISPR-Cas9 genome editing technology